Simvastatin acid-d6 [CAS 2747915-75-7]
Simvastatin acid-d6 [CAS 2747915-75-7]
SKU:QM-0004525
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Product Details
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Description
Simvastatin acid-d6 (Tenivastatin-d6) is deuterium labeled Simvastatin acid. Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin , is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
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CAS Number
[2747915-75-7]
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Molecular Formula
C25H34D6O6
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Molecular Weight
442.62
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Smiles
O=C(O)C[C@H](O)C[C@H](O)CC[C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@H](OC(C(CC)(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)[C@]12[H]
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Target
HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)
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Shipping Conditions
Room temperature
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Simvastatin acid-d6 [CAS 2747915-75-7]
Simvastatin acid-d6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.