Simvastatin acid-d9 (ammonium)
Simvastatin acid-d9 (ammonium)
SKU:QM-0103307
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Product Details
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Description
Simvastatin acid-d9 ammonium is deuterated labeled Simvastatin acid ammonium. Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
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Molecular Formula
C24H32D9NO6
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Molecular Weight
448.64
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Smiles
C[C@@H]1C[C@H](OC([C@@]([2H])(C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])=O)[C@@]2([H])C(C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC([O-])=O)=C1.[NH4+]
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Target
HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Simvastatin acid-d9 (ammonium)
Simvastatin acid-d9 (ammonium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.