Sivelestat (sodium) [CAS 150374-95-1]
Sivelestat (sodium) [CAS 150374-95-1]
SKU:QM-0154566-01
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Product Details
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Description
Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19[1][2][3][4].
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CAS Number
[150374-95-1]
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Molecular Formula
C20H21N2NaO7S
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Molecular Weight
456.44
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Smiles
CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O[Na])=O)=O)=O)C=C1)=O
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Target
Elastase; SARS-CoV
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Purity
99.77
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Sivelestat (sodium) [CAS 150374-95-1]
Sivelestat (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.