SM-164 (hydrochloride) [CAS 2734174-02-6]
SM-164 (hydrochloride) [CAS 2734174-02-6]
SKU:QM-0152847-01
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Product Details
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Description
SM-164 hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP.
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CAS Number
[2734174-02-6]
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Molecular Formula
C62H85ClN14O6
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Molecular Weight
1157.88
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Smiles
C[C@H](NC)C(N[C@H]1CCCC[C@](CC[C@H]2C(N[C@@H](C3=CC=CC=C3)C4=CN(CCCCC5=CC=C(CCCCN6N=NC([C@@H](NC([C@@H]7CC[C@@](CCCC[C@@H]8NC([C@@H](NC)C)=O)([H])N7C8=O)=O)C9=CC=CC=C9)=C6)C=C5)N=N4)=O)([H])N2C1=O)=O.Cl
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Target
Apoptosis; IAP
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Isoform
CIAP; cIAP-1; cIAP-2
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Purity
99
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Solubility
H2O : ≥ 106 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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SM-164 (hydrochloride) [CAS 2734174-02-6]
SM-164 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.