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Sorafenib (Standard) [CAS 284461-73-0]

Sorafenib (Standard) [CAS 284461-73-0]

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SKU:QM-0081750-01

£89.13 GBP
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  • Description

    Sorafenib (Standard) is the analytical standard of Sorafenib. This product is intended for research and analytical applications. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1].

  • CAS Number

    [284461-73-0]

  • Molecular Formula

    C21H16ClF3N4O3

  • Molecular Weight

    464.83

  • Smiles

    O=C(NC(C=C1)=CC=C1OC2=CC(C(NC)=O)=NC=C2)NC3=CC=C(Cl)C(C(F)(F)F)=C3

  • Target

    Apoptosis; Autophagy; Ferroptosis; FLT3; Raf; Reference Standards; VEGFR

  • Purity

    99.71

  • Storage Conditions

    4°C, sealed storage, away from light and moisture

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0081750-01
5 mgQM-0081750-01
£89.13/ea
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10 mgQM-0081750-02
10 mgQM-0081750-02
£115.00/ea
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25 mgQM-0081750-03
25 mgQM-0081750-03
£205.52/ea
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£205.52/ea £0.00
50 mgQM-0081750-04
50 mgQM-0081750-04
£268.70/ea
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£268.70/ea £0.00
100 mgQM-0081750-05
100 mgQM-0081750-05
£356.18/ea
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£356.18/ea £0.00

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Sorafenib (Standard) [CAS 284461-73-0]

Sorafenib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.