SOS1/EGFR-IN-1 [CAS 2956724-20-0]
SOS1/EGFR-IN-1 [CAS 2956724-20-0]
SKU:QM-0152538-01
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Product Details
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Description
SOS1/EGFR-IN-1 (compound SE-9) is a dual-target inhibitor for the prostate cancer. SOS1/EGFR-IN-1 inhibits effectively SOS1 (IC50=42.13±1.55 nM) and EGFR (IC50=1.01±0.04 nM) by inhibiting their downstream effector molecules. SOS1/EGFR-IN-1 induces apoptosis and G1 phase cell cycle arrest, reducing angiogenesis and migration. SOS1/EGFR-IN-1 shows significant antitumor effects in prostate cancer cells PC-3 (IC50=0.45±0.03 μM) [1].
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CAS Number
[2956724-20-0]
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Molecular Formula
C22H24FN3O3
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Molecular Weight
397.44
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Smiles
FC1=CC([C@@H](C)NC2=C3C=C(OC4CCOCC4)C(OC)=CC3=NC=N2)=CC=C1
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Target
EGFR; Ras; SOS1
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Purity
99.54
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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SOS1/EGFR-IN-1 [CAS 2956724-20-0]
SOS1/EGFR-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.