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Spliceostatin A [CAS 391611-36-2]

Spliceostatin A [CAS 391611-36-2]

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SKU:QM-0073729-01

£576.80 GBP
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  • Description

    Spliceostatin A, the FR901464 methylated derivative, is a potent anti-tumor agent. Spliceostatin A inhibits splicing and promotes pre-mRNA accumulation by binding SF3B1. SF3B1 is a subcomplex of U2 small nuclear ribonucleoprotein in the spliceosome. Spliceostatin A induces Apoptosis in chronic lymphocytic leukemia (CLL) cells[1][2][3].

  • CAS Number

    [391611-36-2]

  • Molecular Formula

    C28H43NO8

  • Molecular Weight

    521.64

  • Smiles

    C[C@H]1C[C@@H](NC(/C=C\[C@@H](OC(C)=O)C)=O)[C@@H](C)O[C@H]1C/C=C(C)/C=C/[C@@H]2[C@@H](O)[C@]3(CO3)C[C@@](C)(OC)O2

  • Target

    SF3B1

  • Purity

    95.09

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -80°C, protect from light

  • Shipping Conditions

    Dry Ice

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
100 µgQM-0073729-01
100 µgQM-0073729-01
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1 mgQM-0073729-02
1 mgQM-0073729-02
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£1,395.00
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£1,958.25/ea
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£1,395.00
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5 mgQM-0073729-03
5 mgQM-0073729-03
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£3,114.90
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£4,280.11/ea
£0.00
Regular price
£3,114.90
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Spliceostatin A [CAS 391611-36-2]

Spliceostatin A is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.