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SR12813 (Standard) [CAS 126411-39-0]
SR12813 (Standard) [CAS 126411-39-0]
SKU:QM-0002038
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Product Details
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Description
SR12813 (Standard) is the analytical standard of SR12813. This product is intended for research and analytical applications. SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM[1][2]. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR).
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CAS Number
[126411-39-0]
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Molecular Formula
C24H42O7P2
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Molecular Weight
504.53
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Smiles
OC1=C(C(C)(C)C)C=C(/C=C(P(OCC)(OCC)=O)/P(OCC)(OCC)=O)C=C1C(C)(C)C
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Target
Autophagy; HMG-CoA Reductase (HMGCR) ; Pregnane X Receptor (PXR) ; Reference Standards
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Shipping Conditions
Room temperature
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SR12813 (Standard) [CAS 126411-39-0]
SR12813 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.