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STAT1/3-IN-1 [CAS 2958649-56-2]

STAT1/3-IN-1 [CAS 2958649-56-2]

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QM-0009465-01

£508.06 GBP
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Product Details

  • Description

    STAT1/3-IN-1 (Compound 6k) is a STAT1/3 phosphorylation inhibitor. STAT1/3-IN-1 inhibits the phosphorylation and nuclear translocation of STAT1/3. STAT1/3-IN-1 also inhibits inflammatory enzymes iNOS and COX-2. STAT1/3-IN-1 demonstrates anti-inflammatory effect (reduction of pro-inflammatory cytokines, including IL-1β, IL-6 and TNF-α) without significant cytotoxicity[1].

  • CAS Number

    [2958649-56-2]

  • Molecular Formula

    C28H25ClN6O5

  • Molecular Weight

    560.99

  • Smiles

    ClC1=C(N2C=C(C3=CC=CC(NC(C4=CN(C[C@@](OCC[C@H]5C)([H])N5C6=O)C6=C(OC)C4=O)=O)=C3)N=N2)C=CC=C1

  • Target

    COX; Interleukin Related; NO Synthase; STAT

  • Isoform

    COX-2; IL-6; iNOS; STAT1; STAT3

  • Purity

    99.23

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0009465-01
5 mgQM-0009465-01
£508.06/ea		 £0.00
£508.06/ea £0.00
10 mM - 1 mLQM-0009465-02
10 mM - 1 mLQM-0009465-02
£614.98/ea		 £0.00
£614.98/ea £0.00
10 mgQM-0009465-03
10 mgQM-0009465-03
£783.86/ea		 £0.00
£783.86/ea £0.00
25 mgQM-0009465-04
25 mgQM-0009465-04
£1,518.93/ea		 £0.00
£1,518.93/ea £0.00
50 mgQM-0009465-05
50 mgQM-0009465-05
£2,403.45/ea		 £0.00
£2,403.45/ea £0.00
100 mgQM-0009465-06
100 mgQM-0009465-06
£3,815.28/ea		 £0.00
£3,815.28/ea £0.00
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STAT1/3-IN-1 [CAS 2958649-56-2]

STAT1/3-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.