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STAT3/HDAC-IN-2
STAT3/HDAC-IN-2
SKU:QM-0126394
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Product Details
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Description
STAT3/HDAC-IN-2 (compound 18) is a dual inhibitor of STAT3 and HDAC, inducing autophagy and apoptosis. STAT3/HDAC-IN-2 is an amphiphilic hydroxamic acid hybrid based on the natural product isopropanol lactone (IAL) and is a nanoscale anticancer agent. STAT3/HDAC-IN-2 can self-assemble in water to form nanoparticles, which have higher tumor tissue accumulation, cellular uptake and anticancer properties compared to the free state[1].
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Molecular Formula
C28H32N2O7
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Molecular Weight
508.56
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Smiles
O=C(NO)/C=C/C1=CC=C(C(N[C@H](C)C(O[C@H]2C([C@@](C[C@@](C(C(O3)=O)=C)([H])[C@@]3([H])C4)([H])[C@]4(C)CC2)=C)=O)=O)C=C1
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Target
HDAC; STAT
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Shipping Conditions
Room temperature
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STAT3/HDAC-IN-2
STAT3/HDAC-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.