STAT3-IN-25 [CAS 2591440-75-2]
STAT3-IN-25 [CAS 2591440-75-2]
SKU:QM-0152967-01
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Product Details
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Description
STAT3-IN-25 (Compound 2p) is a potent STAT3 inhibitor with a p-trifluoroethoxy benzyl substituent. STAT3-IN-25 shows STAT3 luciferase inhibition activity using HEK293T cells with an IC50 of 22.3 nM and ATP production inhibition activity using BxPC-3 cells with an IC50 of 32.5 nM. STAT3-IN-25 has the potential for pancreatic cancer research[1].
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CAS Number
[2591440-75-2]
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Molecular Formula
C36H29F6N7O4
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Molecular Weight
737.65
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Smiles
O=C(C(N1C)=CC2=C1C=C(OC3=NC=C(C4=NC(C5=CC=C(C(F)(F)F)C=C5)=NO4)N=C3)C=C2)N6CCN(CC7=CC=C(OCC(F)(F)F)C=C7)CC6
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Target
STAT
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Isoform
STAT3
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Purity
99.36
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Solubility
DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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STAT3-IN-25 [CAS 2591440-75-2]
STAT3-IN-25 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.