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STAT3-IN-39 [CAS 3037596-35-0]
STAT3-IN-39 [CAS 3037596-35-0]
SKU:QM-0101560
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Product Details
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Description
STAT3-IN-39 (compound 10K) is an orally active STAT3 inhibitor that exhibits excellent inhibitory activity against STAT3 phosphorylation, with an IC50 of 0.47 μM in NIH-3T3 cells. STAT3-IN-39 inhibits the TGF-β1-induced fibrotic response and blocks the epithelial-mesenchymal transition in A549. STAT3-IN-39 can be utilized in research related to idiopathic pulmonary fibrosis[1].
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CAS Number
[3037596-35-0]
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Molecular Formula
C20H17F3N2O3S
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Molecular Weight
422.42
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Smiles
O=C(C1=CC2=CC=CC=C2S1(=O)=O)N3CCN(CC4=CC(F)=C(F)C=C4F)CC3
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Target
STAT
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Isoform
STAT3
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Shipping Conditions
Room temperature
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STAT3-IN-39 [CAS 3037596-35-0]
STAT3-IN-39 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.