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STAT3-IN-48 [CAS 1313019-65-6]

STAT3-IN-48 [CAS 1313019-65-6]

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SKU:QM-0145696-01

£140.88 GBP
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  • Description

    STAT3-IN-48 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-48 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-48 does not inhibit kinase activity and has anticancer effects[1].

  • CAS Number

    [1313019-65-6]

  • Molecular Formula

    C21H13ClF3N3O2

  • Molecular Weight

    431.8

  • Smiles

    O=C(NC1=CC=C(OC2=CC=C(C#N)C=C2)C=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3

  • Target

    Apoptosis; STAT

  • Isoform

    STAT3

  • Purity

    98.02

  • Solubility

    DMSO : 250 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H319, H413

  • Precautions

    H319, H413

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5 mgQM-0145696-01
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10 mgQM-0145696-02
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25 mgQM-0145696-03
25 mgQM-0145696-03
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50 mgQM-0145696-04
50 mgQM-0145696-04
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STAT3-IN-48 [CAS 1313019-65-6]

STAT3-IN-48 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.