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STAT3-IN-49
STAT3-IN-49
SKU:QM-0016040
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Product Details
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Description
STAT3-IN-49 (compound B16) is a potent and selective STAT3 inhibitor. STAT3-IN-49 binds to the SH2 domain of STAT3, thereby suppressing its phosphorylation and nuclear translocation. STAT3-IN-49 inhibits triple-negative breast cancer (TNBC) cell migration, invasion, and colony formation. STAT3-IN-49 inhibits tumor growth in an MDA-MB-231 xenograft mouse model. STAT3-IN-49 can be used for TNBC research[1].
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Molecular Formula
C21H19N3O5
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Molecular Weight
393.39
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Smiles
O=C(C1=C2ON=C1C3=CC=C(OCCN4CCNCC4)C=C3)C5=C(C2=O)C=CO5
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Target
STAT
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Isoform
STAT3
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Shipping Conditions
Room temperature
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STAT3-IN-49
STAT3-IN-49 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.