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STAT5-IN-3
STAT5-IN-3
SKU:QM-0009637
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Product Details
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Description
STAT5-IN-3 (Compound 14a) is a STAT5 inhibitor with anticancer activity. STAT5-IN-3 blocks the tyrosine phosphorylation of STAT5A/5B at the Y694/699 sites and significantly reduces the expression of STAT5B protein, thereby inhibiting downstream gene transcription and blocking the proliferation and survival of leukemia cells. Additionally, STAT5-IN-3 holds significant value in overcoming chemotherapy resistance[1].
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Molecular Formula
C25H27N5O
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Molecular Weight
413.51
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Smiles
CC(CC1)(C)C2=C(C=CC=C2C3=CN=C(N)N=C3)N1CCOC4=CC=C5C(C=CN5)=C4
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Target
STAT
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Shipping Conditions
Room temperature
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STAT5-IN-3
STAT5-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.