Sunitinib (Malate) (Standard) [CAS 341031-54-7]
Sunitinib (Malate) (Standard) [CAS 341031-54-7]
SKU:QM-0081897-01
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Product Details
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Description
Sunitinib (Malate) (Standard) is the analytical standard of Sunitinib (Malate) . This product is intended for research and analytical applications. Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2].
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CAS Number
[341031-54-7]
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Molecular Formula
C26H33FN4O7
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Molecular Weight
532.56
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Smiles
O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C.O=C([C@H](CC(O)=O)O)O
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Target
Apoptosis; Autophagy; IRE1; Mitophagy; PDGFR; Reference Standards; VEGFR
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Purity
97.16
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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Sunitinib (Malate) (Standard) [CAS 341031-54-7]
Sunitinib (Malate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.