SV119 (hydrochloride) [CAS 913816-12-3]
SV119 (hydrochloride) [CAS 913816-12-3]
SKU:QM-0014483
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Product Details
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Description
SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM. SV119 hydrochloride enhances the efficient transport of drugs across the plasma membrane of cancer cells. The conjugation of dm-Erastin with SV119 hydrochloride successfully overcomes the internalization barrier observed in pancreatic cancer, while preserving the inherent anti-tumor activity of Erastin. Additionally, SV119 hydrochloride demonstrates cytotoxic effects on triple-negative breast cancer (TNBC) cells and induces apoptosis[1][2].
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CAS Number
[913816-12-3]
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Molecular Formula
C23H39Cl2N3O3
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Molecular Weight
476.48
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Smiles
NCCCCCCN([C@@]1([H])C2)[C@](CCC1)([H])C[C@H]2OC(NC(C=C3C)=C(C=C3)OC)=O.Cl.Cl
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Target
Apoptosis; Sigma Receptor
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Shipping Conditions
Room temperature
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SV119 (hydrochloride) [CAS 913816-12-3]
SV119 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.