Tamoxifen [CAS 10540-29-1]
Tamoxifen [CAS 10540-29-1]
SKU:QM-0146047-01
Couldn't load pickup availability
Request quote or documents
![Tamoxifen [CAS 10540-29-1]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively[5]. Tamoxifen activates autophagy and induces apoptosis[4]. Tamoxifen can also be dissolved in corn oil for use in inducing gene knockout in CreER transgenic mice. (Note: The solution should be prepared protected from light, freshly made before use, and storage is not recommended.). Tamoxifen has better solubility in corn oil compared to Tamoxifen Citrate (HY-13757) [6].
-
CAS Number
[10540-29-1]
-
Molecular Formula
C26H29NO
-
Molecular Weight
371.51
-
Smiles
CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(C=C3)OCCN(C)C
-
Target
Apoptosis; Autophagy; Estrogen Receptor/ERR; HSP
-
Isoform
Estrogen receptor; HSP90
-
Purity
99.96
-
Solubility
DMSO : 13.46 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)
-
Storage Conditions
4°C (Powder, protect from light)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H302, H350, H360, H410
-
Precautions
H302, H350, H360, H410
Related Products
- QM-0015916 Wee1/HDAC-IN-1 [CAS 3037071-29-4]
- QM-0013795-01 Vizenpistat [CAS 2687222-58-6]
- QM-0008932 VEGFR-IN-7 [CAS 683235-33-8]
- QM-0008931 VEGFR-IN-6 [CAS 683235-34-9]
- QM-0008885 VEGFR/PDGFR-IN-1 [CAS 342785-98-2]
- QM-0008364-01 Verubecestat (Standard) [CAS 1286770-55-5]
- QM-0007272 Zavondemstat (sodium) [CAS 2908753-07-9]
- QM-0002491-01 Ziritaxestat (Standard) [CAS 1628260-79-6]
- QM-0002017 Zabadinostat (Standard) [CAS 934828-12-3]
- QM-0079654-01 Zabadinostat [CAS 934828-12-3]
Other industry favorites
- QM-0015916 Wee1/HDAC-IN-1 [CAS 3037071-29-4]
- QM-0013795-01 Vizenpistat [CAS 2687222-58-6]
- QM-0154836-01 Verdiperstat [CAS 890655-80-8]
- QM-0142135-01 Virstatin [CAS 88909-96-0]
- QM-0130840 Versipelostatin [CAS 477201-98-2]
- QM-0073471 VEGFR-IN-4 [CAS 3000483-29-1]
- QM-0081529-01 Ziritaxestat [CAS 1628260-79-6]
- QM-0205620-01 VEGFR-3/FLT4, Mouse (HEK293, hFc)
- QM-0178627-01 VinylMyristate (stabilizedwithMEHQ) [CAS 5809-91-6]
- QM-0175073-01 [Nle8] Somatostatin (1-28) (TFA)
Tamoxifen [CAS 10540-29-1]
Tamoxifen is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.