Tandutinib (hydrochloride) (Standard) [CAS 2438900-70-8]
Tandutinib (hydrochloride) (Standard) [CAS 2438900-70-8]
SKU:QM-0002529-01
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Product Details
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Description
Tandutinib (hydrochloride) (Standard) is the analytical standard of Tandutinib (hydrochloride) . This product is intended for research and analytical applications. Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML) [1][2]. Tandutinib hydrochloride has the ability to cross the blood-brain barrier[3].
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CAS Number
[2438900-70-8]
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Molecular Formula
C31H43ClN6O4
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Molecular Weight
599.16
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Smiles
O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5.Cl
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Target
Apoptosis; c-Kit; FLT3; PDGFR; Reference Standards
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Shipping Conditions
Room temperature
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Tandutinib (hydrochloride) (Standard) [CAS 2438900-70-8]
Tandutinib (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.