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Tanomastat [CAS 179545-77-8]
Tanomastat [CAS 179545-77-8]
SKU:QM-0060095
£125.13 GBP
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Product Details
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Description
Tanomastat (BAY 12-9566) is an orally bioavailable, non-peptidic biphenyl matrix metalloproteinases (MMPs) inhibitor with a Zn-binding carboxyl group. The Ki values are 11, 143, 301, and 1470 nM for MMP-2, MMP-3, MMP-9, MMP-13 respectively. Tanomastat shows anti-invasive and antimetastatic activity in several experimental tumor models[1][2][3].
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CAS Number
[179545-77-8]
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Molecular Formula
C23H19ClO3S
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Molecular Weight
410.91
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Smiles
ClC1=CC=C(C2=CC=C(C(C[C@H](CSC3=CC=CC=C3)C(O)=O)=O)C=C2)C=C1
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Target
MMP
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Isoform
MMP-13; MMP-2; MMP-3; MMP-9
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Purity
99.7
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H312, H332
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Precautions
H302, H312, H332
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Tanomastat [CAS 179545-77-8]
Tanomastat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.