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TAS4464 (hydrochloride) [CAS 1848959-11-4]

TAS4464 (hydrochloride) [CAS 1848959-11-4]

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SKU:QM-0142454-01

£275.99 GBP
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  • Description

    TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1]. TAS4464 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • CAS Number

    [1848959-11-4]

  • Molecular Formula

    C21H24ClFN6O6S

  • Molecular Weight

    542.97

  • Smiles

    NC1=NC=NC2=C1C(C#CC3=C(F)C=CC=C3OCC)=CN2[C@@H]4O[C@H](CNS(=O)(N)=O)[C@@H](O)[C@H]4O.Cl

  • Target

    NEDD8-activating Enzyme

  • Purity

    98.91

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H319

  • Precautions

    H315, H319

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Variant Variant total Quantity Price Variant total
5 mgQM-0142454-01
5 mgQM-0142454-01
£275.99/ea
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10 mM - 1 mLQM-0142454-02
10 mM - 1 mLQM-0142454-02
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10 mgQM-0142454-03
10 mgQM-0142454-03
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25 mgQM-0142454-04
25 mgQM-0142454-04
£777.78/ea
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£777.78/ea £0.00
50 mgQM-0142454-05
50 mgQM-0142454-05
£1,279.58/ea
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£1,279.58/ea £0.00
100 mgQM-0142454-06
100 mgQM-0142454-06
£2,159.24/ea
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TAS4464 (hydrochloride) [CAS 1848959-11-4]

TAS4464 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.