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Tefinostat [CAS 914382-60-8]
Tefinostat [CAS 914382-60-8]
SKU:QM-0112177-01
£414.50 GBP
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Product Details
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Description
Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1) . Tefinostat can be used for the research of leukaemias[1].
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CAS Number
[914382-60-8]
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Molecular Formula
C28H37N3O5
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Molecular Weight
495.61
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Smiles
O=C(OC1CCCC1)[C@H](C2=CC=CC=C2)NCC3=CC=C(NC(CCCCCCC(NO)=O)=O)C=C3
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Target
Apoptosis; HDAC
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Isoform
HDAC
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Purity
99.65
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Tefinostat [CAS 914382-60-8]
Tefinostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.