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Telaglenastat [CAS 1439399-58-2]

Telaglenastat [CAS 1439399-58-2]

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QM-0140548-01

£94.75 GBP
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Product Details

  • Description

    Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity[1].

  • CAS Number

    [1439399-58-2]

  • Molecular Formula

    C26H24F3N7O3S

  • Molecular Weight

    571.57

  • Smiles

    O=C(NC1=NN=C(CCCCC2=NN=C(NC(CC3=CC=CC(OC(F)(F)F)=C3)=O)C=C2)S1)CC4=NC=CC=C4

  • Target

    Autophagy; Glutaminase

  • Purity

    99.92

  • Solubility

    DMSO : 35 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0140548-01
5 mgQM-0140548-01
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0140548-02
10 mM - 1 mLQM-0140548-02
£111.63/ea		 £0.00
£111.63/ea £0.00
10 mgQM-0140548-03
10 mgQM-0140548-03
£129.63/ea		 £0.00
£129.63/ea £0.00
50 mgQM-0140548-04
50 mgQM-0140548-04
£388.99/ea		 £0.00
£388.99/ea £0.00
100 mgQM-0140548-05
100 mgQM-0140548-05
£614.98/ea		 £0.00
£614.98/ea £0.00
500 mgQM-0140548-06
500 mgQM-0140548-06
£1,744.92/ea		 £0.00
£1,744.92/ea £0.00
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Telaglenastat [CAS 1439399-58-2]

Telaglenastat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.