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Temuterkib (Standard) [CAS 1951483-29-6]

Temuterkib (Standard) [CAS 1951483-29-6]

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SKU:QM-0002405

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  • Description

    Temuterkib (Standard) is the analytical standard of Temuterkib. This product is intended for research and analytical applications. Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.

  • CAS Number

    [1951483-29-6]

  • Molecular Formula

    C22H27N7O2S

  • Molecular Weight

    453.56

  • Smiles

    O=C(C(C=C(C1=NC(NC2=CC=NN2C)=NC=C1)S3)=C3C4(C)C)N4CCN5CCOCC5

  • Target

    ERK; Reference Standards

  • Shipping Conditions

    Room temperature

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Temuterkib (Standard) [CAS 1951483-29-6]

Temuterkib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.