Tenofovir exalidex (Standard) [CAS 911208-73-6]
Tenofovir exalidex (Standard) [CAS 911208-73-6]
SKU:QM-0003514
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Product Details
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Description
Tenofovir exalidex (Standard) is the analytical standard of Tenofovir exalidex. This product is intended for research and analytical applications. Tenofovir exalidex (CMX157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. Tenofovir exalidex is active against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available and has no apparent toxicity. Tenofovir exalidex also shows antiviral activity against HBV[1][2][3].
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CAS Number
[911208-73-6]
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Molecular Formula
C28H52N5O5P
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Molecular Weight
569.72
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Smiles
NC1=C2N=CN(C[C@H](OCP(O)(OCCCOCCCCCCCCCCCCCCCC)=O)C)C2=NC=N1
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Target
HBV; HIV; Nucleoside Antimetabolite/Analog; Reference Standards
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Shipping Conditions
Room temperature
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Tenofovir exalidex (Standard) [CAS 911208-73-6]
Tenofovir exalidex (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.