Tenovin-6 (Hydrochloride) [CAS 1011301-29-3]
Tenovin-6 (Hydrochloride) [CAS 1011301-29-3]
SKU:QM-0151617-01
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Product Details
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Description
Tenovin-6 Hydrochloride, an analog of Tenovin-1 , is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH)[2].
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CAS Number
[1011301-29-3]
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Molecular Formula
C25H35ClN4O2S
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Molecular Weight
491.09
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Smiles
O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2.Cl
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Target
Autophagy; Dihydroorotate Dehydrogenase; MDM-2/p53; Sirtuin
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Isoform
SIRT1; SIRT2; SIRT3
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Purity
98.88
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Solubility
DMSO : ≥ 49 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
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Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
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Tenovin-6 (Hydrochloride) [CAS 1011301-29-3]
Tenovin-6 (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.