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Thailanstatin D [CAS 1609105-89-6]
Thailanstatin D [CAS 1609105-89-6]
SKU:QM-0146547-01
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Product Details
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Description
Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis[1].
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CAS Number
[1609105-89-6]
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Molecular Formula
C28H41NO8
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Molecular Weight
519.63
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Smiles
C[C@@H](C[C@H]([C@H](O1)C)NC(/C=C\[C@H](C)OC(C)=O)=O)[C@@H]1C/C=C(C)/C=C/[C@@H]2C[C@@]3(C[C@H](O2)CC(O)=O)CO3
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Target
Apoptosis; DNA/RNA Synthesis
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Thailanstatin D [CAS 1609105-89-6]
Thailanstatin D is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.