Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride) [CAS 2341841-02-7]
Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride) [CAS 2341841-02-7]
SKU:QM-0145380-01
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Product Details
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Description
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].
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CAS Number
[2341841-02-7]
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Molecular Formula
C17H19ClN4O6
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Molecular Weight
410.81
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Smiles
O=C(NCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.[H]Cl
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
99.3
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride) [CAS 2341841-02-7]
Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.