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Thalidomide-5-NH-PEG5-NH2 (hydrochloride)
Thalidomide-5-NH-PEG5-NH2 (hydrochloride)
SKU:QM-0072245
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Quantity
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Product Details
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Description
Thalidomide-5-NH-PEG5-NH2 hydrochloride is the Thalidomide -based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-NH-PEG5-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].
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Molecular Formula
C25H37ClN4O9
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Molecular Weight
573.04
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Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(NCCOCCOCCOCCOCCOCCN)C=C3C2=O)=O)=O.Cl
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
95.84
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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Thalidomide-5-NH-PEG5-NH2 (hydrochloride)
Thalidomide-5-NH-PEG5-NH2 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.