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Thalidomide-5-O-C14-NH2 (hydrochloride)
Thalidomide-5-O-C14-NH2 (hydrochloride)
SKU:QM-0150089-01
£753.49 GBP
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Product Details
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Description
Thalidomide-5-O-C14-NH2 hydrochloride is the Thalidomide -based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C14-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].
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Molecular Formula
C27H40ClN3O5
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Molecular Weight
522.08
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Smiles
O=C1C(C=CC(OCCCCCCCCCCCCCCN)=C2)=C2C(N1C(CC3)C(NC3=O)=O)=O.Cl
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
97.7
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Thalidomide-5-O-C14-NH2 (hydrochloride)
Thalidomide-5-O-C14-NH2 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.