Thalidomide-5-O-C2-NH2 (hydrochloride) [CAS 2694727-89-2]
Thalidomide-5-O-C2-NH2 (hydrochloride) [CAS 2694727-89-2]
SKU:QM-0150073-01
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Product Details
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Description
Thalidomide-5-O-C2-NH2 hydrochloride is the Thalidomide -based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].
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CAS Number
[2694727-89-2]
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Molecular Formula
C15H16ClN3O5
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Molecular Weight
353.76
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Smiles
O=C(CCC1N2C(C(C=CC(OCCN)=C3)=C3C2=O)=O)NC1=O.Cl
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
99.55
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
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Thalidomide-5-O-C2-NH2 (hydrochloride) [CAS 2694727-89-2]
Thalidomide-5-O-C2-NH2 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.