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Thalidomide-piperidine-O-azetidine-acetic acid
Thalidomide-piperidine-O-azetidine-acetic acid
SKU:QM-0106610
Price on request
Quantity
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Product Details
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Description
Thalidomide-piperidine-O-azetidine-acetic acid is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. Thalidomide-piperidine-O-azetidine-acetic acid can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Molecular Formula
C23H26N4O7
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Molecular Weight
470.48
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Smiles
O=C1NC(CCC1N2C(C3=C(C=CC(N4CCC(CC4)OC5CN(C5)CC(O)=O)=C3)C2=O)=O)=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Thalidomide-piperidine-O-azetidine-acetic acid
Thalidomide-piperidine-O-azetidine-acetic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.