Theaflavin-3-gallate (Standard) [CAS 30462-34-1]
Theaflavin-3-gallate (Standard) [CAS 30462-34-1]
SKU:QM-0162334
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Product Details
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Description
Theaflavin-3-gallate (Standard) is the analytical standard of Theaflavin-3-gallate. This product is intended for research and analytical applications. Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner. Theaflavin-3-gallate induces apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells through p53-dependent pathways. Theaflavin-3-gallate induces DNA damage through ATM/Chk/p53 pathway[1][2].
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CAS Number
[30462-34-1]
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Molecular Formula
C36H28O16
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Molecular Weight
716.6
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Smiles
O=C(O[C@H]1[C@@H](C(C=C2O)=CC3=C([C@@H]4[C@H](O)CC5=C(O)C=C(O)C=C5O4)C=C(O)C(O)=C3C2=O)OC6=CC(O)=CC(O)=C6C1)C7=CC(O)=C(O)C(O)=C7
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Target
Apoptosis; ATM/ATR; Checkpoint Kinase (Chk) ; MDM-2/p53; Reference Standards
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Shipping Conditions
Room temperature
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Theaflavin-3-gallate (Standard) [CAS 30462-34-1]
Theaflavin-3-gallate (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.