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Thiocolchicine [CAS 2730-71-4]

Thiocolchicine [CAS 2730-71-4]

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QM-0139009-01

£63.82 GBP
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Product Details

  • Description

    Thiocolchicine, a derivative modified in the C Ring of Colchicine with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 μM) and competitively binds to tubulin with a Ki of 0.7 μM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

  • CAS Number

    [2730-71-4]

  • Molecular Formula

    C22H25NO5S

  • Molecular Weight

    415.5

  • Smiles

    CC(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(SC)C2=O)=O

  • Target

    Apoptosis; Microtubule/Tubulin

  • Purity

    99.77

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H300+H330-H318-H340

  • Precautions

    P260-P264-P270-P271-P280-P284-P304+P340-P305+P351+P338-P330-P403+P233-P405-P501
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Variant Variant total Quantity Price Variant total
5 mgQM-0139009-01
5 mgQM-0139009-01
£46.80
£63.82/ea
 £0.00
£46.80
£63.82/ea
 £0.00
10 mgQM-0139009-02
10 mgQM-0139009-02
£74.70
£118.38/ea
 £0.00
£74.70
£118.38/ea
 £0.00
25 mgQM-0139009-03
25 mgQM-0139009-03
£148.50
£250.47/ea
 £0.00
£148.50
£250.47/ea
 £0.00
50 mgQM-0139009-04
50 mgQM-0139009-04
£242.10
£376.83/ea
 £0.00
£242.10
£376.83/ea
 £0.00
100 mgQM-0139009-05
100 mgQM-0139009-05
£386.10
£571.24/ea
 £0.00
£386.10
£571.24/ea
 £0.00
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Thiocolchicine [CAS 2730-71-4]

Thiocolchicine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.