Thromboxane B2 [CAS 54397-85-2]
Thromboxane B2 [CAS 54397-85-2]
SKU:QM-0058714
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Product Details
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Description
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Thromboxane B2 is a biological inactive product and circulating catabolite of thromboxane A2. Thromboxane B2 levels in peripheral venous blood and coronary sinus blood can be used as a diagnostic marker for angina. Thromboxane B2 level in serum is also associated with inhibition of COX-1 activity inhibition in platelets. Thromboxane B2 is a major product of prostaglandin endoperoxide metabolism. Thromboxane B2 produces dose-related decreases in airflow rate, tidal volume and dynamic lung compliance, whilst simultaneously increasing pulmonary airway resistance in dog model. Thromboxane B2 appears to be a naturally occurring bronchoactive metabolite in the bioconversion of arachidonic acid[1][2][3].
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CAS Number
[54397-85-2]
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Molecular Formula
C20H34O6
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Molecular Weight
370.48
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Smiles
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C[C@@H]1O
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Target
Prostaglandin Receptor
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Purity
99
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Thromboxane B2 [CAS 54397-85-2]
Thromboxane B2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.