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TIE-2/VEGFR-2 kinase-IN-4 [CAS 433224-29-4]

TIE-2/VEGFR-2 kinase-IN-4 [CAS 433224-29-4]

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SKU:QM-0072518

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  • Description

    TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 5.2 nM and 5.1 nM, respectively. TIE-2/VEGFR-2 kinase-IN-4 can be used for the research of angiogenesis[1].

  • CAS Number

    [433224-29-4]

  • Molecular Formula

    C26H17F4N5O4

  • Molecular Weight

    539.44

  • Smiles

    O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C=C2)OC3=CC4=C(N=C(N4)NC(C5=CC=CO5)=O)C=C3

  • Target

    Tie; VEGFR

  • Isoform

    Tie2; VEGFR2/KDR/Flk-1

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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TIE-2/VEGFR-2 kinase-IN-4 [CAS 433224-29-4]

TIE-2/VEGFR-2 kinase-IN-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.