Tilorone (dihydrochloride) [CAS 27591-69-1]
Tilorone (dihydrochloride) [CAS 27591-69-1]
SKU:QM-0159329-01
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Product Details
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Description
Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS[1][2][3].Tilorone dihydrochloride exhibits an inhibitory activity with EC50 of 230 nM against Ebola virus (EBOV) [4].
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CAS Number
[27591-69-1]
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Molecular Formula
C25H36Cl2N2O3
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Molecular Weight
483.47
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Smiles
O=C1C2=C(C3=C1C=C(OCCN(CC)CC)C=C3)C=CC(OCCN(CC)CC)=C2.[H]Cl.[H]Cl
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Target
HIF/HIF Prolyl-Hydroxylase; Influenza Virus
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Purity
99.94
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Solubility
DMSO : 12.5 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H312, H315, H319, H332, H335, H351
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Precautions
H302, H312, H315, H319, H332, H335, H351
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Tilorone (dihydrochloride) [CAS 27591-69-1]
Tilorone (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.