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Tizanidine (Standard) [CAS 51322-75-9]

Tizanidine (Standard) [CAS 51322-75-9]

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SKU:QM-0093989

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  • Description

    Tizanidine (Standard) is the analytical standard of Tizanidine. This product is intended for research and analytical applications. Tizanidine, a skeletal muscle relaxant, is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).

  • CAS Number

    [51322-75-9]

  • Molecular Formula

    C9H8ClN5S

  • Molecular Weight

    253.71

  • Smiles

    ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1

  • Target

    Adrenergic Receptor; Akt; Apoptosis; Reference Standards; Wnt; β-catenin

  • Purity

    90

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

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Tizanidine (Standard) [CAS 51322-75-9]

Tizanidine (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.