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Topiroxostat [CAS 577778-58-6]

Topiroxostat [CAS 577778-58-6]

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QM-0149836-01

£62.26 GBP
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Product Details

  • Description

    Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%) . Topiroxostat has the potential for hyperuricemia treatment[1][2].

  • CAS Number

    [577778-58-6]

  • Molecular Formula

    C13H8N6

  • Molecular Weight

    248.24

  • Smiles

    N#CC1=NC=CC(C2=NNC(C3=CC=NC=C3)=N2)=C1

  • Target

    Cytochrome P450; Xanthine Oxidase

  • Isoform

    CYP3

  • Concentration

    10mM

  • Purity

    99.95

  • Solubility

    DMSO : 23.5 mg/mL (ultrasonic; warming)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0149836-01
5 mgQM-0149836-01
£62.26/ea		 £0.00
£62.26/ea £0.00
10 mgQM-0149836-02
10 mgQM-0149836-02
£89.13/ea		 £0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0149836-03
10 mM - 1 mLQM-0149836-03
£95.88/ea		 £0.00
£95.88/ea £0.00
25 mgQM-0149836-04
25 mgQM-0149836-04
£121.75/ea		 £0.00
£121.75/ea £0.00
50 mgQM-0149836-05
50 mgQM-0149836-05
£223.75/ea		 £0.00
£223.75/ea £0.00
100 mgQM-0149836-06
100 mgQM-0149836-06
£333.10/ea		 £0.00
£333.10/ea £0.00
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Topiroxostat [CAS 577778-58-6]

Topiroxostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.