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Topiroxostat-d4 [CAS 2732868-49-2]
Topiroxostat-d4 [CAS 2732868-49-2]
SKU:QM-0149841-01
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Product Details
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Description
Topiroxostat-d4 is deuterium labeled Topiroxostat. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%) . Topiroxostat has the potential for hyperuricemia treatment[1][2].
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CAS Number
[2732868-49-2]
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Molecular Formula
C13H4D4N6
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Molecular Weight
252.27
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Smiles
N#CC1=NC=CC(C2=NN=C(C3=C([2H])C([2H])=NC([2H])=C3[2H])N2)=C1
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Target
Cytochrome P450; Isotope-Labeled Compounds; Xanthine Oxidase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topiroxostat-d4 [CAS 2732868-49-2]
Topiroxostat-d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.