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Topotecan (hydrochloride hydrate) [CAS 1044663-62-8]
Topotecan (hydrochloride hydrate) [CAS 1044663-62-8]
SKU:QM-0063226
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Product Details
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Description
Topotecan hydrochloride hydrate is an orally active and potent Topoisomerase I inhibitor. Topotecan hydrochloride hydrate induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan hydrochloride hydrate shows anticancer activity[1].
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CAS Number
[1044663-62-8]
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Molecular Formula
C23H26ClN3O6
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Molecular Weight
475.92
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Smiles
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.Cl.O
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Target
Apoptosis; Autophagy; Topoisomerase
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Isoform
Topo I
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topotecan (hydrochloride hydrate) [CAS 1044663-62-8]
Topotecan (hydrochloride hydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.