Tracazolate (hydrochloride) [CAS 1135210-68-2]
Tracazolate (hydrochloride) [CAS 1135210-68-2]
SKU:QM-0160121-01
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Product Details
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Description
Tracazolate (ICI 136753) hydrochloride is a potent GABAA receptor modulator. Tracazolate hydrochloride has selectivity for β3 and potentiates α1β1γ2s (EC50=13.2 μM), α1β3γ2 (EC50=1.5 μM) . Tracazolate hydrochloride has the potency (EC50) determined by the nature of the third subunit (γ1-3, δ, ε) within the receptor complex. Tracazolate hydrochloride possesses anxiolytic and anticonvulsant activity[1][2].
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CAS Number
[1135210-68-2]
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Molecular Formula
C16H25ClN4O2
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Molecular Weight
340.85
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Smiles
O=C(C1=C(C)N=C(N(CC)N=C2)C2=C1NCCCC)OCC.[H]Cl
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Target
GABA Receptor
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Purity
99.24
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Solubility
DMSO : ≥ 125 mg/mL
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Tracazolate (hydrochloride) [CAS 1135210-68-2]
Tracazolate (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.