Trans-Cyclohexane-1,2-diol (Standard) [CAS 1460-57-7]
Trans-Cyclohexane-1,2-diol (Standard) [CAS 1460-57-7]
SKU:QM-0048030
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Product Details
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Description
Trans-Cyclohexane-1,2-diol (Standard) is the analytical standard of trans-Cyclohexane-1,2-diol. This product is intended for research and analytical applications. trans-Cyclohexane-1,2-diol (TCHD) is a transient dilator of the nuclear pore complex (NPC). By interacting with the hydrophobic core (FG nucleoporin) of the NPC, trans-Cyclohexane-1,2-diol can disrupt the NPC structure and reversibly increase the permeability of the nuclear pore, allowing macromolecules larger than 40 kDa (such as plasmid DNA) to enter the cell nucleus by passive diffusion, thereby enhancing the nuclear import efficiency of non-viral vectors. trans-Cyclohexane-1,2-diol can improve the efficiency of in vitro electrotransfection or lipid-mediated gene transfection, especially significantly increasing gene expression in differentiated airway epithelial cells[1][2].
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CAS Number
[1460-57-7]
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Molecular Formula
C6H12O2
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Molecular Weight
116.16
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Smiles
O[C@H]1[C@H](O)CCCC1
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Target
Endogenous Metabolite; Reference Standards
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Shipping Conditions
Room temperature
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Trans-Cyclohexane-1,2-diol (Standard) [CAS 1460-57-7]
Trans-Cyclohexane-1,2-diol (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.