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Trimebutine (maleate) (Standard) [CAS 34140-59-5]

Trimebutine (maleate) (Standard) [CAS 34140-59-5]

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SKU:QM-0119764-01

£116.13 GBP
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  • Description

    Trimebutine maleate (Standard) is the analytical standard of Trimebutine maleate. This product is intended for research and analytical applications. Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine maleate inhibits L-type Ca2+ channels and large-conductance calcium-activated potassium channels (BKCa channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine maleate also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine maleate also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine maleate also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS)[2][3][4][5][6].

  • CAS Number

    [34140-59-5]

  • Molecular Formula

    C26H33NO9

  • Molecular Weight

    503.54

  • Smiles

    O=C(O)/C=C\C(O)=O.O=C(OCC(C1=CC=CC=C1)(N(C)C)CC)C2=CC(OC)=C(OC)C(OC)=C2

  • Target

    Akt; Apoptosis; Calcium Channel; ERK; IRAK; JNK; NF-κB; Opioid Receptor; Potassium Channel; Reference Standards; Toll-like Receptor (TLR)

  • Isoform

    ERK1; ERK2; IRAK1; L-type calcium channel; μ Opioid Receptor/MOR

  • Shipping Conditions

    Room temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0119764-01
5 mgQM-0119764-01
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£72.90
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£116.13/ea
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10 mgQM-0119764-02
10 mgQM-0119764-02
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£120.60
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£212.81/ea
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£120.60
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25 mgQM-0119764-03
25 mgQM-0119764-03
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£232.20
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£363.47/ea
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£232.20
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50 mgQM-0119764-04
50 mgQM-0119764-04
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£358.20
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£533.57/ea
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Regular price
£358.20
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100 mgQM-0119764-05
100 mgQM-0119764-05
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£521.10
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£753.49/ea
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Regular price
£521.10
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£753.49/ea
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Trimebutine (maleate) (Standard) [CAS 34140-59-5]

Trimebutine (maleate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.