Trimebutine (Standard) [CAS 39133-31-8]
Trimebutine (Standard) [CAS 39133-31-8]
SKU:QM-0115352-01
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Product Details
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Description
Trimebutine (Standard) is the analytical standard of Trimebutine. This product is intended for research and analytical applications. Trimebutine is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. Trimebutine inhibits L-type Ca2+ channels and large-conductance calcium-activated potassium channels (BKCa channels), thereby inhibiting extracellular calcium influx and potassium ion efflux. Trimebutine also targets Toll-like receptors, inhibits Toll-like receptor 2/4/7/8/9 signals, and inhibits LPS-induced IRAK1 activation, as well as ERK1/2, JNK and NF-κB activation, thereby exerting anti-inflammatory effects. Trimebutine also induces tumor cell apoptosis by inhibiting the AKT/ERK pathway. Trimebutine also inhibits excessive contraction of smooth muscle and can be used in the study of gastrointestinal disorders such as irritable bowel syndrome (IBS)[2][3][4][5][6].
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CAS Number
[39133-31-8]
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Molecular Formula
C22H29NO5
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Molecular Weight
387.47
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Smiles
O=C(OCC(C1=CC=CC=C1)(N(C)C)CC)C2=CC(OC)=C(OC)C(OC)=C2
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Target
Akt; Apoptosis; Calcium Channel; ERK; IRAK; JNK; NF-κB; Opioid Receptor; Potassium Channel; Reference Standards; Toll-like Receptor (TLR)
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Isoform
ERK1; ERK2; IRAK1; L-type calcium channel; μ Opioid Receptor/MOR
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Shipping Conditions
Room temperature
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Trimebutine (Standard) [CAS 39133-31-8]
Trimebutine (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.