Trimethylamine-N-oxide-13C3
Trimethylamine-N-oxide-13C3
SKU:QM-0138809
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Product Details
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Description
Trimethylamine-N-oxide-13C3 is the 13C-labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway[1][2][3].
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Molecular Formula
13C3H9NO
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Molecular Weight
78.09
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Smiles
[13CH3][N+]([13CH3])([O-])[13CH3]
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Target
Endogenous Metabolite; Isotope-Labeled Compounds; NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS) ; TGF-beta/Smad
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Trimethylamine-N-oxide-13C3
Trimethylamine-N-oxide-13C3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.