Trimethylamine N-oxide-d9 [CAS 1161070-49-0]
Trimethylamine N-oxide-d9 [CAS 1161070-49-0]
SKU:QM-0059208-01
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Product Details
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Description
Trimethylamine N-oxide-d9 is the deuterium labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway[1][2][3].
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CAS Number
[1161070-49-0]
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Molecular Formula
C3D9NO
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Molecular Weight
84.17
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Smiles
[2H]C([2H])([N+](C([2H])([2H])[2H])([O-])C([2H])([2H])[2H])[2H]
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Target
Endogenous Metabolite; NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS) ; TGF-beta/Smad
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Purity
99.76
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Solubility
DMSO : 100mg/mL (ultrasonic) |H2O : 100mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Trimethylamine N-oxide-d9 [CAS 1161070-49-0]
Trimethylamine N-oxide-d9 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.