Trimipramine [CAS 739-71-9]
Trimipramine [CAS 739-71-9]
SKU:QM-0075211
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Product Details
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Description
Trimipramine is a 5-HT receptor antagonist, with pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively. Trimipramine is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 μM, 2.11 μM, 3.72 μM, 8.00 μM, respectively. Trimipramine has vascular activity and anxiolytic efficacy[1][2][3].
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CAS Number
[739-71-9]
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Molecular Formula
C20H26N2
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Molecular Weight
294.43
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Smiles
CC(CN1C2=CC=CC=C2CCC3=C1C=CC=C3)CN(C)C
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Target
5-HT Receptor; Bacterial
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Isoform
5-HT1 Receptor; mLAG-3; α-1 microglobulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H225-H301+H311+H331-H370
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Precautions
P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
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Trimipramine [CAS 739-71-9]
Trimipramine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.