Trovafloxacin (Standard) [CAS 147059-72-1]
Trovafloxacin (Standard) [CAS 147059-72-1]
SKU:QM-0088728
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Product Details
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Description
Trovafloxacin (Standard) is the analytical standard of Trovafloxacin. This product is intended for research and analytical applications. Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1[1][2][3].
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CAS Number
[147059-72-1]
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Molecular Formula
C20H15F3N4O3
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Molecular Weight
416.35
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Smiles
O=C(C1=CN(C2=CC=C(F)C=C2F)C3=NC(N4C[C@@]5([H])[C@H](N)[C@@]5([H])C4)=C(F)C=C3C1=O)O
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Target
Antibiotic; Bacterial; Reference Standards; Topoisomerase
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Shipping Conditions
Room temperature
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Trovafloxacin (Standard) [CAS 147059-72-1]
Trovafloxacin (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.