Tryptamine [CAS 61-54-1]
Tryptamine [CAS 61-54-1]
SKU:QM-0160368-01
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Product Details
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Description
Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist (EC50=1-3 mM) and an endogenous ligand of the aryl hydrocarbon receptor (AHR) (Kd=10-50 nM) . Tryptamine promotes intestinal anion secretion and fluid transport by activating G protein-coupled receptors (GPCRs) and accelerates gastrointestinal motility. Tryptamine regulates Th17/Treg balance to inhibit neuroinflammation, competitively binds to 5-HT receptors to regulate central nervous system activity, and participates in temperature regulation and spinal reflex regulation as a neuromodulator. Tryptamine can be used to study intestinal motility disorders such as functional constipation, and has shown significant efficacy in multiple sclerosis models[1][2][3].
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CAS Number
[61-54-1]
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Molecular Formula
C10H12N2
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Molecular Weight
160.22
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Smiles
NCCC1=CNC2=C1C=CC=C2
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Target
5-HT Receptor; Aryl Hydrocarbon Receptor; Endogenous Metabolite
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Isoform
Microbial Metabolite
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Purity
99.95
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Solubility
DMSO : ≥ 150 mg/mL
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H318, H335
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Precautions
H302, H315, H318, H335
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Tryptamine [CAS 61-54-1]
Tryptamine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.